First impressions based purely on the trailers:
Asatte no Houkou: Looks sweet enough but the moe quota could be too much for me to stomach.
Ayakashi Ayashi: An historical-looking effort, which could be a nice change. Reminds me to check out Otogi Zoshi on DVD asap.
Black Blood Brothers: Screams "Style over substance!" but I have to admit it does have style. The 80s guitar solo and vampiric overtones win bonus points in my book.
Black Lagoon: The Second Barrage: Tough guys! Tough gals! Guns! More guns! Why did I miss the first season? I won't be making the same mistake twice.
Busou Renkin: A bit too 'swords and sorcery' for my liking...the sakura blossoms don't bode well either. Still undecided.
Code Geass: It has mecha, which is a good sign. It has CLAMP's name in the opening titles. Possibly very good.
D.Gray Man: I concur that this looks darned cool.
Death Note: Top of the list. I don't even need to look at the trailer - I already know this is going to be excellent.
Ghost Hunt: I prefer realism and science fiction over the supernatural - there probably won't be room for this in my viewing schedule.
Kanon Prelude: I'm not keen on the cutesy character designs but the slcie of life genre often leaves me pleasantly surprised once I get into the story.
Katekyo Hitman Reborn!: Not my thing AT ALL. Sorry.
Kekkaishi: See above.
Negima: Doesn't look like my thing either, but I enjoyed the Love Hina manga. Possibly good.
Pumpkin Scissors: Dark, angsty, military. I'll try that one first.
Red Garden: Hard to say what the storyline will be but it certainly looks good. Then there's Gonzo's notoriously mixed track record to consider...cautiously optimistic.
Soukou no Strain: CGI looks a little overpowering but this was the studio that made Crest of the Stars iirc. I'll keep my eyes and ears open for how it turns out.
Super Robot Taisen OG ~Divine Wars~: More mecha! I'll give it a shot sometime on that reason alone.
The Galaxy Railways 2nd Season: Since I never saw the first season I don't think it'll be worth my while. Visually though it looks pretty interesting.
Venus Versus Virus: Nice imagery but it looks a little to 'style over substance'-ish for my liking.
Yamato Nadeshiko Shichihenge: Could be good for a laugh. Possibly.
In summary, Black Lagoon, Pumpkin Scissors, Red Garden and Ayakashi Ayashi will probably be the only ones I'll actually have the time to watch. It goes without saying that Death Note will make my world go round all over again of course, but combined with my lethal cocktail of DVDs, full time work and part time uni studies there won't be enough hours in the day for any more!