Which version of it? I've only actually watched the old one so far and it's been a while.
I guess the show is kind of a good example of the way that anime is more than just cartoons for kids and can deal with a variety of subjects including some fairly serious ones (while still being fairly accessible and fairly young people friendly). I probably wouldn't have gotten into anime as much if it hadn't been one of the first shows I watched and while Fullmetal Alchemist has quite a range itself I've found there's even more variety out there than I could have imagined.
If the above makes any sense, you could probably translate it into some catchier and more to the point phrase (something that I'm bad at, if you haven't noticed).