(Time for me to be flamed)
FMA (The first series) was for me, the biggest dissapointment I have had in anime bar none. I had heard a synopsis of the story and the dark fantasy theme sounded right up my street. So I went and watched it.
Put it bluntly it was one of the most unpleasant experiences I have seen in any genre.
The problem? It is dark story, lots of emotional problems to play out, and what did they do? they presented it as a comedy.
After the first few episodes dealing with literally dozens of 'short people' jokes I stopped watching an have never gone back. A little in keeping humour? fine. Completely over the top slapstick in a serious story? No thanks.
Yes I know this is just my opinion. And no I am not just a grump - I find Excel Saga hilarious for one, but that is properly a comedy. The story of FMA is NOT a comedy, to play it as one was a travesty to the story. Equally I have no idea if the manga is played the same way. Doesn't matter, it clashes horribly for me.
*Moan over*